|distributed.net Faq-O-Matic : the Client software : What about a core for the GPUs in video accelerator cards?|
There are various clients available that support crunching on GPUs using hardware that is capable of general purpose computing. A separate client is needed to run on the GPU. Only the RC5 project is current supported on GPUs.
Clients utilizing Nvidia CUDA, ATI Stream are available. The more modern universal OpenCL interface is available in clients as well and supports running on Nvidia, AMD and Intel GPU hardware and any other hardware that supports OpenCL.
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